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Genetic Cause of Glioblastoma Pinpointed
A new study from scientists at Columbia University Medical Center pinpoints the genetic cause of glioblastoma and found that drugs that target the protein produced...
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New Biomarker for Skin Cancer Discovered
Scientists at Harvard-affiliated Brigham and Women’s Hospital have discovered a new biomarker for melanoma, finding that certain biochemical elements in the DNA of normal pigment-producing...
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Unique Drug Combinations Show Positive Results in Fighting Late-Stage Melanoma
Using novel high-throughput screening techniques to overcome the problems of resistance and partial response to single-drug cancer therapy in patients with melanoma, Yale scientists identified...
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UCSF Researchers Discover a New Type of Pluripotent Cell in Breast Tissue
Scientists at UC San Francisco discovered that rare somatic cells extracted from human breast tissue are pluripotent cells that could play an important role in...
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Cancer Scientists Prove Long-Standing Theory on How Cancer Spreads
A newly published study shows that white blood cells and cancer cells can fuse and initiate a tumor, providing the first proof in humans of...
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Scientists Uncover a Pathway for Silencing Tumor Suppressor Genes
Researchers have identified a RAS-regulated pathway that initiates and maintains the epigenetic silencing of tumor suppressor genes in mice, a finding that may help provide...
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New Method for Detecting Unwanted DNA Breaks in Human Cells
Researchers at the Harvard Medical School have developed a new method for detecting unwanted DNA breaks across the entire genome of human cells induced by...
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Researchers Uncover Genetic Trigger for Immune Response
Yale researchers have identified an unexpected relationship between mtDNA and the innate immune response, showing a new source of inflammation that could promote common diseases...
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Yale Scientists Reveal ‘Major Player’ in Skin Cancer Genes
Researchers from Yale University have confirmed that a gene known as NF1 is a “major player” in the development of skin cancer. A multidisciplinary team...
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Scientists Produce Photoreceptors from Embryonic Stem Cells
By producing photoreceptors from human embryonic stem cells, researchers from the University of Montreal have taken a major step forward in the fight against age-related...
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Genetically Reducing AMPK Activity May Prevent Hereditary Hearing Loss
New research from Yale University reveals that genetically reducing AMPK activity delays hereditary hearing loss in mice. Hereditary hearing loss can worsen over time and...
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Study Shows Amateur Contact Sports Increase Risk of Degenerative Disorder
Past evidence has shown that professional football players are susceptible to a progressive degenerative disease, chronic traumatic encephalopathy (CTE), which is caused by repetitive brain...
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Yale Researchers Identify Gene That Regulates the Growth of Melanoma
New research from Yale University identifies a gene in melanoma that can dramatically affect the growth of the disease. The findings, published in the journal...
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Yale Study Shows Gut Bacteria Aggressively Protect Their Territory
A newly published study from Yale University details how human gut bacteria take on many tasks crucial to health. Bacterially speaking, it gets very crowded...
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Study Reveals a Promising New Target to Treat Type 2 Diabetes
Scientists at Yale University reveal promising new target for drugs to treat type 2 diabetes. When the body’s cells don’t respond normally to insulin —...
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Yale Researchers Reveal Genes Behind Aggressive Ovarian and Endometrial Cancers
Researchers from Yale University have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas, pointing the way to possible new treatments. The findings...
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Researchers Find Antibody That ‘Neutralizes’ Zika Virus
A team of researchers has isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. The antibody, called...
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New Study Reveals Why Some People Develop Progressive Multiple Sclerosis
A team of researchers has uncovered two closely related cytokines — molecules involved in cell communication and movement — that may explain why some people...
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Wolf-Sized Prehistoric Otter Had a Surprisingly Powerful Bite
A newly published study reveals that a massive, wolf-sized otter that lived about 6 million years ago may have been a dominant predator in its...
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Monkeys and Humans Share Same Signs of Alzheimer’s
Very old rhesus monkeys exhibit similar patterns of brain pathology as human Alzheimer’s patients, researchers report in the journal Alzheimer’s & Dementia: The Journal of...
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Shining Molecules Detect Tau Pathology in Alzheimer’s Disease
Small shining molecules developed by scientists at Linköping University in Sweden can be designed to distinguish between plaque of different proteins in the brain. They...
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Biologists Develop Breakthrough RNA-Based Therapy to Target West Nile Virus
A Yale-led research team developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus. The innovative approach reduced...
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Artificial Intelligence Model Can Successfully Predict the Reoccurrence of...
A deep learning model trained to analyze histological images of surgical specimens accurately classified patients with and without Crohn’s disease recurrence, investigators report in The...
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A Reality Check – When Lab-Trained AI Meets the Real World, “Mistakes Can...
Contamination of tissue samples can mislead AI models, preventing them from making accurate diagnoses in real-world situations. Human pathologists undergo rigorous training to identify instances...
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